The National Hurricane Center said the warning is in effect for areas between the South Santee River in South Carolina to Duck, North Carolina.
A Hurricane Watch is in effect for Edisto Beach, South Carolina to the South Santee River, and from Duck, North Carolina to the Virginia border.
People all along the southeastern and mid-Atlantic states should keep an eye on the storm, the NHC said.
On Wednesday morning, the center of Hurricane Florence was located 575 miles off of Cape Fear, North Carolina moving toward the west-northwest near 17 mph.
Florence’s eye became a little ragged in appearance on satellite images Tuesday night, but recently it has become better defined. There has also been a little cooling of the tops surrounding the eye.
On the forecast track, the center of Florence will move over the southwestern Atlantic Ocean between Bermuda and the Bahamas Wednesday, and approach the coast of North Carolina or South Carolina in the hurricane warning area on Thursday and Friday.
Florence is expected to slow down considerably. By overnight Friday into Saturday morning, the center of the storm may still be off the Outer Banks. It could be a Category 2 by the time it makes landfall. While this may lessen wind speeds by landfall, it could increase rainfall totals to as much as 40 inches in North Carolina.